Comparative analysis of genomes allows to uncover the biology of microorganisms, such as how they adapt to different hosts, disseminate in time and space or acquire genetic traits that confer virulence or resistance to antibiotics. Our lab leads local and international initiatives to study established and emerging pathogens like Campylobacter, Leptospira or Clostridioides.
The role of the microbiome in human and animal health is today questionless. However, its variation in different populations need to be explored more in depth. Our work is focused on determining the composition and variability of the human microbiome in Latin America guided by an one-health approach, given that we also pay attention to the environment in which we live.
Development of tools and methods
The field of microbial genomics demands of constant development and update of bioinformatic tools to meet new analytical needs. Our work focuses on the development of new software and protocols for the comparative analysis of bacterial genomes and metagenomes, particularly for data produced by new third-generation sequencing technologies like Oxford Nanopore.